Alexei Vyssotski

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My research interests are focused on understanding of the brain function in birds. In particular, I am interested in studying of navigation and memory processes, related to it. I investigate brain activity in freely moving animals, both in naturalistic and lab settings in order to elucidate electro-physiological correlates of different complex behavioral processes - orientation, decision making, inter-subject interactions and, since recently, influence of the social context and other factors on vocal leaning in young zebra finches.






  • Amendola, E and Zhan, Y and Mattucci, C and Castroflorio, E and Calcagno, E and Fuchs, C and Lonetti, G and Silingardi, D and Vyssotski, AL and Farley, D and Ciani, E and Pizzorusso, T and Giustetto, M and Gross, CT Mapping pathological phenotypes in a mouse model of CDKL5 disorder., PLoS One, 9:(5), 2014
  • Anisimov, Victor N and Herbst, Joshua A and Abramchuk, Andrei N and Latanov, Alexander V and Hahnloser, Richard H R and Vyssotski, Alexei L Reconstruction of vocal interactions in a group of small songbirds, Nature Methods(11) 1135–1137, 2014
  • Baker, R and Gent, TC and Yang, Q and Parker, S and Vyssotski, AL and Wisden, W and Brickley, SG and Franks, NP Altered activity in the central medial thalamus precedes changes in the neocortex during transitions into both sleep and propofol anesthesia., J Neurosci., 34:(40) 13326-13335, 2014
  • Duriez, O and Kato, A and Tromp, C and Dell'Omo, G and Vyssotski, AL and Sarrazin, F and Ropert-Coudert, Y. How cheap is soaring flight in raptors? A preliminary investigation in freely-flying vultures., PLoS One, 9:(1), 2014
  • Gelegen, C and Gent, TC and Ferretti, V and Zhang, Z and Yustos, R and Lan, F and Yang, Q and Overington, DW and Vyssotski, AL and van Lith, HA and Wisden, W and Franks, NP. Staying awake--a genetic region that hinders α2 adrenergic receptor agonist-induced sleep., Eur J Neurosci., 40:(1) 2311-9, 2014
  • Scriba, MF and Rattenborg, NC and Dreiss, AN and Vyssotski, AL and Roulin, A. Sleep and vigilance linked to melanism in wild barn owls., J Evol Biol., 27:(10) 2057-68, 2014
  • Voirin, B and Scriba, MF and Martinez-Gonzalez, D and Vyssotski, AL and Wikelski, M and Rattenborg, NC. Ecology and neurophysiology of sleep in two wild sloth species., Sleep, 37:(4) 753-61, 2014
  • Yu, X and Zecharia, A and Zhang, Z and Yang, Q and Yustos, R and Jager, P and Vyssotski, AL and Maywood, ES and Chesham, JE and Ma, Y and Brickley, SG and Hastings, MH and Franks, NP and Wisden, W. Circadian Factor BMAL1 in Histaminergic Neurons Regulates Sleep Architecture., Curr Biol., 24:(23) 2838-44, 2014
  • Zhan, Y and Paolicelli, RC and Sforazzini, F and Weinhard, L and Bolasco, G and Pagani, F and Vyssotski, AL and Bifone, A and Gozzi, A and Ragozzino, D and Gross, CT. Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior., Nat Neurosci., 17:(3) 400-6, 2014



  • Lesku, J.A. and Meyer, L.C. and Fuller, A. and Maloney, S.K. and Dell'Omo, G. and Vyssotski, A.L and Rattenborg, N.C. Ostriches sleep like platypuses, PLoS One, 6:(8) e23203, 2011
  • Lesku, J.A. and Vyssotski, A.L. and Martinez-Gonzalez, D. and Wilzeck, C. and Rattenborg, N.C. Local sleep homeostasis in the avian brain: convergence of sleep function in mammals and birds?, Proceedings of the Royal Society B: Biological Sciences, 278:(1717) 2419-2428, 2011
  • Scheffzük, C. and Kukushka, V.I. and Vyssotski, A.L. and Draguhn, A. and Tort, A.B.I. and Brankack, J. Selective Coupling between Theta Phase and Neocortical Fast Gamma Oscillations during REM-Sleep in Mice, PLoS One, 6:(12) e28489, 2011
  • Tsoar, A. and Nathan, R. and Bartan, Y. and Vyssotski, A. and Dell'Omo, G. and Ulanovsky, N. Large-scale navigational map in a mammal, Proceedings of the National Academy of Sciences, 108:(37) E718-E724, 2011


  • Brankack, J and Kukushka, V I and Vyssotski, A L and Draguhn, A EEG gamma frequency and sleep–wake scoring in mice: Comparing two types of supervised classifiers, Brain Research, 1322: 59-71, 2010 pdf